Current Project Samples
Orthopedic Surgery
ACL Signal Intensity at 2 years postoperative is related to poor graft alignment and increased symptoms.
Improved data collection protocols
Using a patient-specific, imaging-acquired hip joint center, lower limb biomechanical measures show improved reliability and sensitivity to change.
Clinical Validation
Imaging Accessibility
Intervertebral discs demonstrate a shape change in response to a simple rotation mobilization, explaining part of the symptomatic improvements.
Imaging Accessibility
Transdisciplinary Research
Imaging Accessibility
Cartilage composition may be deduced with ultrasound using a combination of echo-intensity and thickness change in response to load.
Imaging Reliability
Transdisciplinary Research
Transdisciplinary Research
By understanding the constant and variable differences in quantitative imaging values between scanners, studies can be more reliably compared, even with difference hardware.
Transdisciplinary Research
Transdisciplinary Research
Transdisciplinary Research
Even with optimal biomechanical intervention (surgery, bracing, weight loss), presence of inflammatory factors may limit the response to treatment in knee osteoarthritis.
Past Project Samples
Transdisciplinary Research
Innovative Surgical Approaches
Transdisciplinary Research
Lower limb realignment surgery for knee osteoarthritis reduces inflammation proportional to the changes in joint loading.
Orthopedic Surgery
Innovative Surgical Approaches
Transdisciplinary Research
Lower limb realignment surgery improves cartilage health and symptoms without affecting other areas of the joint.
Innovative Surgical Approaches
Innovative Surgical Approaches
Innovative Surgical Approaches
An extra ligament on the lateral side of the knee improves outcomes of ACL reconstruction. Cartilage however may be at risk as a result.
Disease mechanisms
Advanced Mechanistic Research
Innovative Surgical Approaches
Patients at risk for osteoarthritis have a similar cartilage response to walking compared to healthy controls with no risk factors.
Systematic Reviews
Advanced Mechanistic Research
Advanced Mechanistic Research
Patients at risk for knee osteoarthritis have compromised articular cartilage composition compared to healthy controls.
Advanced Mechanistic Research
Advanced Mechanistic Research
Advanced Mechanistic Research
Perfusion of the knee joint with exercise depends on stage of disease and the severity of swelling.